NAD+

Summary

NAD⁺ is studied for its role in cellular energy, DNA repair, and molecular aging. Technically, it is the coenzyme nicotinamide adenine dinucleotide, present in all cells and central to energy production, redox reactions, and cellular signaling; its levels decline with age, making it a key target in longevity research.

Why is it researched?

• •  Cellular energy production (ATP)
• •  DNA repair and sirtuin activity
• •  Mitochondrial function and biogenesis
• •  Molecular aging and longevity

Cycle and break

Mechanism of action

Driver of cellular energy

It acts as a cofactor in glycolysis, the Krebs cycle, and oxidative phosphorylation, transferring electrons in the oxidation-reduction reactions that generate ATP.

DNA repair and sirtuins

It is the substrate for sirtuins and PARP enzymes, involved in DNA repair, chromatin regulation, and mitochondrial biogenesis.

Homeostasis and signaling

It regulates calcium homeostasis pathways, inflammation, and chromatin remodeling.

Scientific evidence

Cellular metabolism: It is one of the most widely used cofactors in cellular metabolism.

Aging: Its decline is associated with increased DNA damage, oxidative stress, and mitochondrial dysfunction in aging models.

NAD⁺ availability: Researched alongside modulators such as 5-Amino-1MQ for its role in NAD⁺ availability.

Product use

NAD⁺ is a central reference material in research on energy metabolism, mitochondria, and longevity. At Peptido BioGenetic, we offer it for research grade, with a certificate of analysis (COA) available upon request.

⚠️ Product intended exclusively for research and laboratory use. Not suitable for human or veterinary consumption.