NAD+

NAD+

Summary

NAD⁺ is studied for its role in cellular energy, DNA repair and molecular aging. Technically, it is the coenzyme nicotinamide adenine dinucleotide, present in every cell and central to energy production, redox reactions and cell signaling; its levels decline with age, which has made it a key target in longevity research.

NAD⁺ is not the same as NAD

“NAD” on its own is the name of the molecule, which exists in the body in two forms: NAD⁺ and NADH. The “+” sign is not decoration: it marks the active form, the one the cell has free to work with.

NAD⁺ · the active form
It collects energy from nutrients and is the form consumed by the enzymes that repair DNA. It is also the form that declines with age.
NADH · the already-loaded form
It carries that energy to the mitochondria. It does not serve as raw material for cellular repair.

This vial contains NAD⁺ as is: not NADH, nor a precursor such as NMN or NR that the body would first have to convert. That is why it is the most researched form, mainly for three reasons: energy (it is essential for producing ATP), repair (it fuels the enzymes that fix DNA) and aging (its levels fall over the years).

What is it researched for?

  • • Cellular energy production (ATP)
  • • DNA repair and sirtuin activity
  • • Mitochondrial function and biogenesis
  • • Molecular aging and longevity

Cycle and break

Cycle
4–8 weeks
Break
2–4 weeks

Mechanism of action

Driver of cellular energy

It acts as a cofactor in glycolysis, the Krebs cycle and oxidative phosphorylation, transferring electrons in the oxidation-reduction reactions that generate ATP.

DNA repair and sirtuins

It is the substrate for sirtuins and PARP enzymes, which are involved in DNA repair, chromatin regulation and mitochondrial biogenesis.

Homeostasis and signaling

It regulates pathways of calcium homeostasis, inflammation and chromatin remodeling.

Scientific evidence

Cellular metabolism: It is one of the most widely used cofactors in cellular metabolism.

Aging: Its decline is associated with greater DNA damage, oxidative stress and mitochondrial dysfunction in aging models.

NAD⁺ availability: Researched alongside modulators such as 5-Amino-1MQ for its role in NAD⁺ availability.

Product use

NAD⁺ is a core reference material in research on energy metabolism, mitochondria and longevity. At Peptido BioGenetic we offer it in research grade, with a certificate of analysis (COA) available on request.

⚠️ Product intended exclusively for research and laboratory use. Not for human or veterinary consumption.

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Recommended for reconstitution

Reconstitution Pack

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≥99% purity
COA available
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Technical information

Technical Specifications

  • Compound NAD⁺ (nicotinamide adenine dinucleotide · beta-NAD)
  • CAS Number 53-84-9
  • Molecular Formula C21H27N7O14P2
  • Molecular Weight 663.4 g/mol
  • Content 1000 mg per vial
  • Form Lyophilized powder (vial)
  • Purity Verified to European laboratory standards · COA available on request

Storage

Short Term
below 4 °C
Long Term
-80 °C
Shelf Life
36 months
NAD+
From €178,90

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