MELANOTAN II

Summary

Melanotan II is one of the most studied peptides in the field of pigmentation and the melanocortin system: it is researched for its role in melanogenesis (melanin production) and melanocortin receptor biology. Technically, it is a cyclic synthetic α-MSH analog and a non-selective agonist of melanocortin receptors (MC1R, MC3R, MC4R, and MC5R).

What is it researched for?

• •  Melanogenesis and skin pigmentation
• •  UV radiation-independent photoprotection
• •  Melanocortin receptor biology
• •  Central signaling via MC4R

Cycle and rest

Mechanism of action

Melanogenesis via MC1R

Activation of the MC1R receptor in melanocytes stimulates eumelanin synthesis, which is the basis for its study in skin pigmentation and photoprotection.

Melanocortin system (MC4R)

As a non-selective agonist, it also acts on MC4R, a pathway involved in appetite regulation and sexual function.

Research in pigmentation

It is researched in the context of pigmentation, photoprotection, and the biology of various melanocortin receptors.

Scientific evidence

Melanogenesis: Studies describe an increase in MC1R-mediated melanogenesis, independent of UV radiation exposure.

Melanocortin system: Preclinical models document effects on the central melanocortin system.

Receptor affinity: Literature describes its affinity for multiple melanocortin receptor subtypes.

Product use

Due to its action on melanogenesis and the melanocortin system, Melanotan II is a prominent reference material in research on pigmentation and melanocortin receptors. At Peptido BioGenetic, we supply it as a high-purity peptide for laboratory use, with a Certificate of Analysis (COA) available upon request.

⚠️ Product intended exclusively for research and laboratory use. Not for human or veterinary consumption.