AOD 9604
Summary
AOD-9604 is studied for its selective fat-burning action: it mobilizes visceral and localized fat without affecting glucose or appetite. Technically, it is a synthetic peptide fragment of the carboxyl terminus of human growth hormone (residues 177-191) with an added tyrosine, designed to preserve the lipolytic action of GH without its effects on growth or glycemia: it mobilizes lipids without elevating IGF-1.
Why is it being researched?
- • Mobilization of visceral and localized fat
- • Lipid metabolism without elevating IGF-1
- • Non-alcoholic fatty liver disease
- • Cartilage preservation and bone density
Cycle and rest
Mechanism of action
Selective lipolysis
It activates hormone-sensitive lipase (HSL), inhibits acetyl-CoA carboxylase, and upregulates the β3-adrenergic receptor, stimulating fat burning without stimulating tissue growth or insulin resistance.
Expanded metabolic profile
It has been investigated beyond fat: non-alcoholic fatty liver, cartilage preservation, and maintenance of bone density in osteoarthritis models.
Documented human safety
It is one of the few peptides of its kind with an extensive clinical history: human trials confirmed a safety profile comparable to placebo and no IGF-1 elevation.
Scientific evidence
Lipolysis: In animal models of obesity, it induced a reduction in body fat without elevating IGF-1 or altering blood glucose.
Metabolic and joint applications: Preclinical data support these metabolic and joint applications.
Safety: Clinical programs with over 900 subjects (2001-2006) established its safety; in the U.S., it has received favorable regulatory status as a research ingredient.
Product use
Due to its selective lipolysis and robust safety history, AOD-9604 is a prominent reference material in lipid metabolism research. At Peptido BioGenetic, we offer it as a high-purity peptide, with a certificate of analysis (COA) available upon request.
⚠️ Product intended exclusively for research and laboratory use. Not suitable for human or veterinary consumption.
Garantía de Pureza >98.5% Analizado independientemente por espectroscopia y pruebas HPLC. Empaque térmico priority incluido en el envío.
Información Clínica
Especificaciones Técnicas
- Compuesto AOD-9604 (Tyr-hGH 177-191, hexadecapéptido)
- Número CAS 221231-10-3
- Fórmula Molecular C78H123N23O23S2
- Peso Molecular ~1815,1 g/mol
- Contenido 10 mg por vial
- Presentación Polvo liofilizado (vial)
- Pureza Verificada según estándares de laboratorio europeos · COA disponible bajo solicitud
