IPAMORELIN

Summary

Ipamorelin is one of the most selective and clean growth hormone secretagogues in somatotropic axis research: it is studied for its role in muscle development and recovery. Technically, it is a pentapeptide (NNC-26-0161), a ghrelin receptor agonist (GHS-R1a) that stimulates GH without elevating cortisol, prolactin, or other hormones.

What is it researched for?

• •  Selective growth hormone release
• •  Muscle development and recovery
• •  GH/IGF-1 axis without elevating cortisol or prolactin
• •  Pharmacological profile of the ghrelin receptor

Cycle and break

Mechanism of action

Selective growth hormone release

It activates the GHS-R1a receptor in the pituitary and hypothalamus, triggers the phospholipase C pathway and calcium entry, and induces GH secretion by inhibiting somatostatin, with an elevation of IGF-1.

Favorable pharmacological profile

Maximum effect on GH in ~40 minutes and a half-life of about 2 hours, making it a benchmark secretagogue in research.

Scientific evidence

Selectivity: its distinct feature is its selectivity: it does not stimulate ACTH, cortisol, prolactin, FSH, LH, or TSH.

Pharmacological profile: its clean profile differentiates it from less selective secretagogues.

Product use

Ipamorelin is a prominent reference material in somatotropic axis research. At Peptido BioGenetic, we offer it as a high-purity peptide for laboratory use, with a certificate of analysis (COA) available upon request.

⚠️ Product intended exclusively for research and laboratory use. Not suitable for human or veterinary consumption.