SS 31
Summary
SS-31 is one of the benchmark peptides in mitochondrial and bioenergetic research: it is studied for its role in protecting mitochondria and cellular energy production. Technically, it is a mitochondrion-targeting tetrapeptide (elamipretide) that selectively binds to cardiolipin in the inner mitochondrial membrane.
Why is it being researched?
- • Mitochondrial function and bioenergetics
- • ATP synthesis and membrane potential
- • Oxidative stress and reactive oxygen species
- • Age-related mitochondrial decline and frailty
Cycle and break
Mechanism of action
Mitochondrial membrane protection
It stabilizes cardiolipin and cristae morphology, preserves membrane potential, and enhances ATP synthesis via oxidative phosphorylation, reducing reactive oxygen species.
Aging and mitochondrial dysfunction
It is being investigated in age-related mitochondrial decline and frailty.
Scientific evidence
Bioenergetics: cardiovascular damage and neuroprotection models support its improvement of cellular bioenergetics.
Clinical development: Elamipretide received FDA approval (2025) for Barth syndrome, a mitochondrial disease.
Product use
SS-31 is a premier reference material in mitochondrial bioenergetics research. At Peptido BioGenetic, we offer it as a high-purity peptide for laboratory use, with a Certificate of Analysis (COA) available upon request.
⚠️ Product intended exclusively for research and laboratory use. Not suitable for human or veterinary consumption.
Recommended for reconstitution
≥99% purity guarantee Independently tested by spectrometry and HPLC.
Technical information
Technical Specifications
- Compound SS-31 / Elamipretide (MTP-131, Bendavia) — D-Arg-Tyr(2,6-diMe)-Lys-Phe
- CAS Number 736992-21-5
- Molecular Formula C32H49N9O5
- Molecular Weight 639.8 g/mol
- Content 20 mg per vial
- Form Lyophilized powder (vial)
- Purity Verified to European laboratory standards · COA available on request