{"product_id":"epithalon-25-mg","title":"EPITHALON","description":"\u003cp style=\"font-size:.8em;letter-spacing:.12em;text-transform:uppercase;color:#9ca3af;font-weight:600;margin:0 0 .4em;font-family:inherit;\"\u003eSummary\u003c\/p\u003e\n\u003cp style=\"font-size:1.05em;line-height:1.65;margin:0 0 1.2em;\"\u003e\u003cstrong\u003eEpithalon\u003c\/strong\u003e is one of the benchmark peptides in research on \u003cstrong\u003elongevity and cellular aging\u003c\/strong\u003e. It is studied for its role in cellular repair, sleep rhythm, and telomere maintenance. Technically, it is a bioregulatory tetrapeptide (sequence AEDG: Ala-Glu-Asp-Gly) derived from pineal gland epithalamin, and one of the few peptides with direct evidence of telomerase activation in human cells.\u003c\/p\u003e\n\n\u003cp style=\"font-size:.8em;letter-spacing:.12em;text-transform:uppercase;color:#9ca3af;font-weight:600;margin:1.9em 0 .6em;font-family:inherit;\"\u003eWhat is it researched for?\u003c\/p\u003e\n\u003cul style=\"margin:0 0 1.2em;padding-left:0;list-style:none;line-height:1.9;\"\u003e\n\n  \u003cli style=\"padding-left:1.3em;text-indent:-1.3em;margin:0;\"\u003e\n\n\u003cspan style=\"color:#0099ff;font-weight:700;\"\u003e•\u003c\/span\u003e  Telomerase activation and telomere maintenance\u003c\/li\u003e\n\n  \u003cli style=\"padding-left:1.3em;text-indent:-1.3em;margin:0;\"\u003e\n\n\u003cspan style=\"color:#0099ff;font-weight:700;\"\u003e•\u003c\/span\u003e  Cellular repair and senescence\u003c\/li\u003e\n\n  \u003cli style=\"padding-left:1.3em;text-indent:-1.3em;margin:0;\"\u003e\n\n\u003cspan style=\"color:#0099ff;font-weight:700;\"\u003e•\u003c\/span\u003e  Circadian rhythm and pineal sleep signaling\u003c\/li\u003e\n\n  \u003cli style=\"padding-left:1.3em;text-indent:-1.3em;margin:0;\"\u003e\n\n\u003cspan style=\"color:#0099ff;font-weight:700;\"\u003e•\u003c\/span\u003e  Antioxidant defense\u003c\/li\u003e\n\n  \u003cli style=\"padding-left:1.3em;text-indent:-1.3em;margin:0;\"\u003e\n\n\u003cspan style=\"color:#0099ff;font-weight:700;\"\u003e•\u003c\/span\u003e  Genomic stability and longevity\u003c\/li\u003e\n\n\n\u003c\/ul\u003e\n\n\u003cp style=\"font-size:.8em;letter-spacing:.12em;text-transform:uppercase;color:#9ca3af;font-weight:600;margin:1.9em 0 .6em;font-family:inherit;\"\u003eCycle and rest\u003c\/p\u003e\n\u003cdiv style=\"display:flex;gap:12px;margin:0 0 1.4em;flex-wrap:wrap;\"\u003e\n\n  \u003cdiv style=\"flex:1;min-width:150px;padding:12px 16px;background:#f6f6f7;border-radius:10px;\"\u003e\n\n    \u003cdiv style=\"font-size:.72em;text-transform:uppercase;letter-spacing:.08em;color:#9ca3af;margin-bottom:2px;\"\u003eCycle\u003c\/div\u003e\n\n    \u003cdiv style=\"font-weight:600;\"\u003e10–20 days\u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n  \u003cdiv style=\"flex:1;min-width:150px;padding:12px 16px;background:#f6f6f7;border-radius:10px;\"\u003e\n\n    \u003cdiv style=\"font-size:.72em;text-transform:uppercase;letter-spacing:.08em;color:#9ca3af;margin-bottom:2px;\"\u003eRest\u003c\/div\u003e\n\n    \u003cdiv style=\"font-weight:600;\"\u003e4–6 months\u003c\/div\u003e\n\n  \u003c\/div\u003e\n\n\n\u003c\/div\u003e\n\n\u003cp style=\"font-size:.8em;letter-spacing:.12em;text-transform:uppercase;color:#9ca3af;font-weight:600;margin:1.9em 0 .6em;font-family:inherit;\"\u003eMechanism of action\u003c\/p\u003e\n\u003cp style=\"margin:1.1em 0 0.3em;font-weight:600;font-family:inherit;\"\u003eTelomerase and telomere maintenance\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.9em;line-height:1.6;\"\u003eIt activates the telomerase enzyme, responsible for rebuilding telomeres (the protective ends of chromosomes that shorten with age), counteracting one of the central markers of cellular aging.\u003c\/p\u003e\n\u003cp style=\"margin:1.1em 0 0.3em;font-weight:600;font-family:inherit;\"\u003eCircadian rhythm and antioxidation\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.9em;line-height:1.6;\"\u003eIt restores pineal signaling (melatonin and serotonin synthesis) and the regularity of the circadian rhythm, and enhances antioxidant defense by reducing reactive oxygen species.\u003c\/p\u003e\n\u003cp style=\"margin:1.1em 0 0.3em;font-weight:600;font-family:inherit;\"\u003eLongevity and genomic stability\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.9em;line-height:1.6;\"\u003eIt regulates chromatin condensation states, T-lymphocyte maturation, and genome stability.\u003c\/p\u003e\n\n\u003cp style=\"font-size:.8em;letter-spacing:.12em;text-transform:uppercase;color:#9ca3af;font-weight:600;margin:1.9em 0 .6em;font-family:inherit;\"\u003eScientific evidence\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.7em;padding:10px 14px;background:#f3f4f6;border-radius:8px;font-size:.92em;color:#4b5563;line-height:1.5;\"\u003e\u003cstrong\u003eTelomerase:\u003c\/strong\u003e In Prof. Khavinson's work, Epithalon activated telomerase and lengthened telomeres in cultured human fibroblasts, surpassing the Hayflick limit of cell divisions.\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.7em;padding:10px 14px;background:#f3f4f6;border-radius:8px;font-size:.92em;color:#4b5563;line-height:1.5;\"\u003e\u003cstrong\u003eCircadian rhythm:\u003c\/strong\u003e Animal models describe normalization of nocturnal melatonin and antioxidant enzymes in aged organisms.\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.7em;padding:10px 14px;background:#f3f4f6;border-radius:8px;font-size:.92em;color:#4b5563;line-height:1.5;\"\u003e\u003cstrong\u003eLongevity:\u003c\/strong\u003e Studies in rodents associated pineal peptides with increased life expectancy and lower tumor incidence; also investigated in Drosophila, primates, and human cultures.\u003c\/p\u003e\n\n\u003cp style=\"font-size:.8em;letter-spacing:.12em;text-transform:uppercase;color:#9ca3af;font-weight:600;margin:1.9em 0 .6em;font-family:inherit;\"\u003eProduct use\u003c\/p\u003e\n\u003cp style=\"margin:0 0 0.9em;line-height:1.6;\"\u003eDue to its demonstrated ability to activate telomerase, Epithalon is a first-rate reference material in senescence and longevity research. At \u003cstrong\u003ePeptido BioGenetic\u003c\/strong\u003e, we offer it as a high-purity peptide for laboratory use, with a Certificate of Analysis (COA) available upon request.\u003c\/p\u003e\n\n\u003cp style=\"margin:1.6em 0 0;padding:12px 14px;background:#f3f4f6;border-radius:8px;font-size:.92em;color:#4b5563;line-height:1.5;\"\u003e⚠️ Product intended exclusively for \u003cstrong\u003eresearch and laboratory use\u003c\/strong\u003e. Not suitable for human or veterinary consumption.\u003c\/p\u003e","brand":"PeptidoBioGenetic","offers":[{"title":"10 mg","offer_id":54545811439945,"sku":"ET10","price":70.87,"currency_code":"EUR","in_stock":false},{"title":"50 mg","offer_id":54603273863497,"sku":"ET50","price":162.49,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1016\/7507\/3865\/files\/epithalon-25-mg-sin-fondo.png?v=1782819718","url":"https:\/\/www.peptidobiogenetic.com\/en-us\/products\/epithalon-25-mg","provider":"PeptidoBioGenetic","version":"1.0","type":"link"}